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Modulation of Choline Transport and Acetylcholine Synthesis in Synaptosomes from Different Brain Regions

โœ Scribed by Nordberg, Agneta ;Sundwall, Anders

Book ID
114800511
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
402 KB
Volume
56
Category
Article
ISSN
0001-6683

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Endogenous free choline levels and acetylcholine (ACh) synthesis in nerve terminals were investigated using cerebral cortical synaptosomes of C57BL/6 mice. Endogenous choline was produced at a rate tenfold faster than ACh to provide levels adequate for the formation of the latter. The combined pool