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Modulation of chemical carcinogen-induced unscheduled DNA synthesis by dehydroepiandrosterone (DHEA) in the primary rat hepatocytes

โœ Scribed by Seung Hee Kim; Hyung-Mee Han; Seog Youn Kang; Ki Kyung Jung; Tae Gyun Kim; Hye Young Oh; Young-Kyung Lee; Hang Mook Rheu

Publisher
Springer
Year
1999
Tongue
English
Weight
434 KB
Volume
22
Category
Article
ISSN
0253-6269

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Modulation of ultraviolet light-, ethyl methanesulfonate-, and 7, 12-dimethylbenz[a]anthracene-induced unscheduled dna synthesis by retinol and retinoic acid in the primary rat hepatocyte
โœ John D. Budroe; Joseph G. Shaddock; Daniel A. Casciano ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 625 KB

The effects of retinol and retinoic acid on unscheduled DNA synthesis (UDS) in primary Sprague-Dawley rat hepatocytes were studied in the presence and absence of known chemical and physical mutagens. Neither retinol nor retinoic acid caused a significant increase in UDS over solvent control at conce