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Modulation of cellular phorbol ester binding and/or protein kinase C activity by human placental fractions

โœ Scribed by Elisabeth Hamel; Jean-Louis Tayot; Hiroshi Yamasaki


Book ID
119120807
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
322 KB
Volume
970
Category
Article
ISSN
0167-4889

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We have shown that platelet-activating factor (PAF), a weak primary stimulus for neutrophil superoxide generation, synergistically enhances neutrophil oxidative responses to the tumor promoter phorbol myristate acetate (PMA). Since PMA is known to cause cytosol-to-membrane shift of calcium-activated