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Modulation of calcium sensitivity in guinea pig taenia coli: skinned fiber studies

✍ Scribed by J. C. Rüegg; G. Pfitzer

Publisher
Springer
Year
1985
Tongue
English
Weight
620 KB
Volume
41
Category
Article
ISSN
1420-682X

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Effects of 2,3-butanedione monoxime on activation of contraction and crossbridge kinetics in intact and chemically skinned smooth muscle fibres from guinea pig taenia coli
✍ Å. Österman; A. Arner; U. Malmqvist 📂 Article 📅 1993 🏛 Springer Netherlands 🌐 English ⚖ 788 KB

The effects of 2,3-butanedione monoxime (BDM) were studied in smooth muscle fibres from guinea pig taenia colt. In intact muscle, active force during contractions induced by high-K + was inhibited by about 10% in I mM BDM and by approximately 70% in 10 mM BDM. Intracellular [Ca 2+ ] during contracti