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Modulation of cadmium chloride toxicity by sulphur amino acids in hepatoma cells

โœ Scribed by George Fotakis; John A. Timbrell

Book ID
116919408
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
197 KB
Volume
20
Category
Article
ISSN
0887-2333

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We observed that all-trans-retinoic acid (RA) down-regulated insulin-like growth factor binding proteins (IGFBPs) in cultured human hepatoma cells (Hep 3B, PLC/PRF/5, and Hep G2); therefore, we characterized the role of this down-regulation in cell growth. Treatment with 10 micromol/L RA revealed a