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Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome

✍ Scribed by Surabi Veeraragavan; Nghiem Bui; Jennie R. Perkins; Lisa A. Yuva-Paylor; Randall L. Carpenter; Richard Paylor


Publisher
Springer
Year
2011
Tongue
English
Weight
286 KB
Volume
217
Category
Article
ISSN
0033-3158

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Deletion of 8.5 Mb, including theFMR1 ge
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A four-year-old boy with severe psychomotor retardation, facial appearance consistent with the fragile X syndrome, hypotonia, and overgrowth was found to have a deletion including the fragile X gene (FMR1). The breakpoints of the deletion were established between CDR1 and sWXD2905 (approximately 200