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Modulation by protein kinase C of nitric oxide and cyclic GMP formation in cultured cerebellar granule cells

✍ Scribed by Antonella Riccio; Ennio Esposito; Maria Luisa Eboli


Book ID
113128409
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
730 KB
Volume
718
Category
Article
ISSN
0006-8993

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Regulation by calcium of the nitric oxid
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Ca2+ entry induced by N-methyl-D-aspartate (NMDA) in neurons and by noradrenaline (NA) in astrocytes is known to increase intracellular cyclic GMP (cGMP) levels through stimulation of the Ca2+-dependent nitric oxide synthase type I (NOS-I). The possibility that Ca2+ entry could also down-regulate in