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Modular Engineering of L-Tyrosine Production in Escherichia coli

✍ Scribed by Juminaga, D.; Baidoo, E. E. K.; Redding-Johanson, A. M.; Batth, T. S.; Burd, H.; Mukhopadhyay, A.; Petzold, C. J.; Keasling, J. D.

Book ID: 123615626
Publisher: American Society for Microbiology
Year: 2011
Tongue: English
Weight: 685 KB
Volume: 78
Category: Article
ISSN: 0099-2240
DOI: 10.1128/AEM.06017-11

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## Abstract L‐Tyrosine (L‐tyr) overproducing __Escherichia coli__ strain derived from an L‐phenylalanine (L‐phe) overproducing strain is characterized in 10 L and 200 L scale fermentations. Deletion of the chromosomal region encoding for the __pheA__ gene, chorismate mutase/prephenate dehydratase,