The measurement of 13,14-dihydro-15-keto
β
R. W. Kelly; M. H. Abel
π
Article
π
1983
π
John Wiley and Sons
π
English
β 360 KB
π 1 views
The main metabolite of prostaglandin E, (PGE2) 13,14-dihydro-Sketo-PGE, readily dehydrates and can subsequently form a cyclic derivative. This problem can be overcome by the immediate formation of oximes of the 9 and 15 ketones in aqueous solution followed by subsequent extraction, methylation and t