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Modified Intercalation Model for the Interaction of Amino Acridines and DNA

✍ Scribed by PRITCHARD, N. J.; BLAKE, A.; PEACOCKE, A. R.


Book ID
109653505
Publisher
Nature Publishing Group
Year
1966
Tongue
English
Weight
221 KB
Volume
212
Category
Article
ISSN
0028-0836

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We present the results of free energy perturbation/molecular dynamics studies on 3-DNA . daunomycin and 3-DNA . 9-aminoacridine complexes as well as on B-DNA itself in order to calculate the free energy differences between complexes having different base pair sequences. The results generally reprodu