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Modified Hyaluronic Acid as A Carrier of Mitomycin C for Ophthalmology

✍ Scribed by Vil’danova, R. R.; Sigaeva, N. N.; Kukovinets, O. S.; Zaidullin, I. S.; Fazylova, G. R.; Kuznetsov, S. I.; Kolesov, S. V.


Book ID
125358250
Publisher
Springer
Year
2014
Tongue
English
Weight
68 KB
Volume
50
Category
Article
ISSN
0009-3130

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The aim of this work was to evaluate the use of thermosensitive hydrogels for intravesical cisplatin delivery into the bladder. Poly(N-isopropylacrylamide) (PNIPAM) was grafted onto hyaluronic acid (HA) to synthesize an HPN copolymer, which was further grafted with gelatin to form an HPNG copolymer.