Gap junctional intercellular communication (GJIC) has been proposed as a cellular mechanism for tumour suppression and there is experimental evidence in support of this. If aberrant GJIC contributes to the formation of human breast tumours, one might expect that the connexins (gap junction proteins)
β¦ LIBER β¦
Modified expression of testicular gap-junction connexin 43 during normal spermatogenic cycle and in altered spermatogenesis
β Scribed by Catharine Batias; Norah Defamie; Abdesselam Lablack; Dominique Thepot; Patrick Fenichl; Dominique Segretain; Georges Pointis
- Publisher
- Springer-Verlag
- Year
- 1999
- Tongue
- English
- Weight
- 376 KB
- Volume
- 298
- Category
- Article
- ISSN
- 0302-766X
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The connexins are a family of proteins that form the intercellular membrane channels of gap junctions. Genes encoding 13 different rodent connexins have been cloned and characterized to date. Connexins vary both in their distribution among adult cell types and in the properties of the channels that