Modified DNA fragments specifically and irreversibly bind transcription factor NF-κB in lysates of human tumor cells
✍ Scribed by M. A. Timchenko; E. Yu. Rybalkina; A. Yu. Lomakin; K. I. Evlakov; I. N. Serdyuk; M. G. Ivanovskaya
- Book ID
- 110153596
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 245 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0006-2979
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The activation of the NF‐κB pathway by pro‐inflammatory cytokines, such as tumor necrosis factor‐α (TNFα), can be an important contributor for the re‐programming of chondrocyte gene expression, thereby making it a therapeutic target in articular diseases. To search for new approaches to
## Abstract We have developed a separation technique for DNA–protein complex based on electrophoretic mobility shift assay (EMSA) by microchip electrophoresis, which we call microchip electrophoretic mobility shift assay (μEMSA). To evaluate the μEMSA, we employed recombinant human nuclear factor‐κ