𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Modifications of ureteric peristalsis by local anaesthetic an experimental study in dogs

✍ Scribed by Struthers, N. W.

Book ID
104689760
Publisher
Springer
Year
1976
Tongue
English
Weight
592 KB
Volume
4
Category
Article
ISSN
0300-5623

No coin nor oath required. For personal study only.

✦ Synopsis

An in vivo study of the response of the dog ureter to local anaesthetics administered systemically and by ureteric perfusion, revealed that lidocaine, procaine, and mepivacaine, caused hyperperistalsis. The intravenous use of a near toxic dose produced hyperperistalsis of limited duration, whereas, intraureteric administration produced a prolonged and constant response with low dosage. The mode of action of these drugs is unclear as they are generally regarded as being non specific smooth muscle depressants. Continued peristalsis after prolonged exposure to local anaesthetic favours a myogenic rather than neurogenic conduction of the ureteric contraction wave.

πŸ“œ SIMILAR VOLUMES

The prophylactic value of cooling strang
The prophylactic value of cooling strangulated herniae locally. An experimental study in dogs
✍ W. J. Boerema; B. N. Catchpole; L. R. Finlay-Jones πŸ“‚ Article πŸ“… 1970 πŸ› John Wiley and Sons 🌐 English βš– 329 KB πŸ‘ 2 views

## Abstract In 10 anaesthetized dogs bilateral groin herniae were created, each containing a loop of small bowel which was strangulated with binding tape. One side was cooled locally, the other acted as a control. After 7 1/2 hours the two loops of bowel were inspected and compared as regards viab