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Modification of the sesquiterpene lactones leukomisin and austricin biological activities of some of their derivatives

✍ Scribed by A. B. Plutno; I. D. Sham'yanov; M. I. Aizikov; M. R. Prokhorova; G. G. Galyust'yan; A. G. Kurmukov


Publisher
Springer
Year
1995
Tongue
English
Weight
485 KB
Volume
31
Category
Article
ISSN
0009-3130

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AbstractÐAmong the hapalosin derivatives synthesized, the compounds carrying methyl (5a), methylthioethyl (5d) and phenylmethyl (5e) groups at the C12 position possess only the cis-peptide structure, in contrast to the cases of 5b and 5c. In addition to their conformational stability, the biological