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Modification of the 4-(p-nitrobenzyl) pyridine assay for measurement of melphalan and mechlorethamine in plasma

✍ Scribed by Joseph L. Skibba; Fred G. Collins

Book ID
119085799
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
578 KB
Volume
4
Category
Article
ISSN
0160-5402

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The average of five replicate determinations for percent intact melphalan in a single vial of dosage formulation was 88.7% with a standard deviation of 1 (range = 2.5 %). Variations of less than 3 % were found in the assay of several vials from the same production lot. The samples and reference sol