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Modification of sickle hemoglobin by acetaldehyde and its effect on oxygenation, gelation and sickling

✍ Scribed by E.C. Abraham; M. Stallings; A. Abraham; G.J. Garbutt

Book ID: 113263904
Publisher: Elsevier Science
Year: 1982
Tongue: English
Weight: 397 KB
Volume: 705
Category: Article
ISSN: 0167-4838
DOI: 10.1016/0167-4838(82)90338-7

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An important purpose of blood transfusion in patients with sickle cell disease is to improve arterial oxygen saturation (SaO 2 ) and thereby reduce red cell sickling. To investigate the degree of improvement in SaO 2 by blood transfusion, we determined the hemoglobin oxygen affinity, transcutaneous