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Modification of polyuridylic acid by bisulfite: Effect on double helix formation and coding properties

✍ Scribed by Robert Shapiro; Barbara Braverman


Book ID
118853623
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
343 KB
Volume
47
Category
Article
ISSN
0006-291X

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Modification of polyuridylic acid by bis
✍ Robert Shapiro; Barbara Braverman; Wlodzimierz Szer πŸ“‚ Article πŸ“… 1973 πŸ› Springer 🌐 English βš– 329 KB

The reaction of polyuridylic acid with sodium bisulfite produces modified polymers in which up to 95% of the uracil residues have been converted to uracil-6-sulfonate residues. A 91.6% bisulfite-saturated polymer was found to resist hydrolysis by spleen phosphodiesterase and phosphorolysis by polynu