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Modification of phospholipid metabolism in dibutyryl-cAMP-mediated morphological conversion of cho cells

โœ Scribed by Elpidio A. Dosado; Abraham W. Hsie; Fred Snyder


Book ID
118311512
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
326 KB
Volume
78
Category
Article
ISSN
0006-291X

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Chinese hamster ovary (CHO) strain 10215 carries a dominant mutation which confers resistant to cAMP by virtue of an altered catalytic subunit of the CAMP-dependent protein kinase (Evain et al., 1979). This mutation was transferred to wild-type CHO cells by DNA-mediated gene transfer. Based on the a