DNA-mediated transfer of cAMP resistance
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Irene Abraham; Steven Brill; Margaret Chapman; Jennifer Hyde; Michael Gottesman
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Article
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1986
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John Wiley and Sons
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English
โ 609 KB
Chinese hamster ovary (CHO) strain 10215 carries a dominant mutation which confers resistant to cAMP by virtue of an altered catalytic subunit of the CAMP-dependent protein kinase (Evain et al., 1979). This mutation was transferred to wild-type CHO cells by DNA-mediated gene transfer. Based on the a