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Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability

โœ Scribed by Yang, Won Ho; Kim, Ji Eun; Nam, Hyung Wook; Ju, Jung Won; Kim, Hoe Suk; Kim, Yu Sam; Cho, Jin Won


Book ID
109912505
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
941 KB
Volume
8
Category
Article
ISSN
1465-7392

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## Abstract The mTOR alpha4 phosphoprotein is a prolactin (PRL)โ€downregulated gene product that is found in the nucleus of PRLโ€dependent rat Nb2 lymphoma cells. Alpha4 lacks a nuclear localization signal (NLS) and the mechanism of its nuclear targeting is unknown. Postโ€translational modification by