Modification of oxidative stress by pioglitazone in the heart of alloxan-induced diabetic rabbits
β Scribed by Anna Gumieniczek
- Publisher
- BioMed Central
- Year
- 2005
- Tongue
- English
- Weight
- 193 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1021-7770
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π SIMILAR VOLUMES
## Abstract ## Background The effects of two drugs representing different classes of antidiabetic pharmacology (pioglitazone, a thiazolidinedione; and metformin, a biguanide) on the myocardial metabolism in the ischemia are poorly understood. ## Methods To test the hypothesis that cardioprotecti
There is considerable evidence that phosphatidate (PA) and Iysophosphatidate (LPA) are important second messengers in sisnal transduotion processes in a variety of nell types. Objecti~s It. To determine the ability of PA and LPA to serve as substrates for the placental, intestinal and tissue nonspee