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Modification of metabolism of transplantable and spontaneous murine tumors by the nitric oxide synthase inhibitor, nitro-L-arginine

✍ Scribed by Pauline J. Wood; Janet M. Sansom; Ian J. Stratford; Gerald E. Adams; Csaba Szabo; Christoph Thiemermann; John R. Vane


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
553 KB
Volume
29
Category
Article
ISSN
0360-3016

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## Abstract **BACKGROUND:** To test whether the differentiating embryo is susceptible to the teratogenic effects of the nitric oxide (NO) synthesis inhibitor N^G^‐nitro‐L‐arginine methyl ester (L‐NAME). **METHODS:** ICR‐(CD‐1) mice received a single intraperitoneal injection of L‐NAME at 90, 150, o