## Abstract Strips of guinea pig ileum lose over 70% of their contractility when bathed in Krebs‐Ringer solution containing 0.4–0.9 M formamide (FMD). This effect is not accompanied by an appreciable loss of tissue water and is totally reversed by washing the preparation in normal solution. Frog sa
✦ LIBER ✦
Modification of excitation-contraction coupling in locust skeletal muscle induced by caffeine
✍ Scribed by Huddart, Henry ;Abram, Roland G.
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- English
- Weight
- 728 KB
- Volume
- 171
- Category
- Article
- ISSN
- 0022-104X
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Central core disease (CCD) and malignant hyperthermia (MH) are skeletal muscle disorders that are linked to mutations in the gene that encodes the type 1 ryanodine receptor (RYR1). The RYR1 ion channel plays a central role in excitation-contraction (EC) coupling by releasing Ca(2+) from an internal