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Modification of ethanol effects by bicuculline: genotype-dependent responses and inheritance

โœ Scribed by Tamara J. Phillips; Bruce C. Dudck

Book ID
104775487
Publisher
Springer
Year
1989
Tongue
English
Weight
806 KB
Volume
98
Category
Article
ISSN
0033-3158

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## Abstract Apurinic/apyrimidinic (AP) sites are common mutagenic and cytotoxic DNA lesions that arise from the loss of normal bases. APE1, the major AP endonuclease of human cells, plays a central role in the repair of AP sites through both its endonuclease and phosphodiesterase activities. A comm