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Modification of dimethylnitrosamine-induced changes in renal metabolism and subsequent effect on carcinogenic activity of actinomycin D and cycloheximide

✍ Scribed by B.W. Stewart; P.N. Magee

Book ID
113145351
Publisher
Elsevier Science
Year
1973
Weight
954 KB
Volume
9
Category
Article
ISSN
0014-2964

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## Abstract Actinomycin D and mitomycin C, inhibitors of DNA‐dependent RNA synthesis, were ineffective in blocking desoxycorticosterone (DOC)‐induced in vitro maturation in oocytes of the catfish, __Heteropneustes fossilis__ (Bloch). This suggests that a concurrent mRNA synthesis is not obligatory