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Modification of Cullin-1 by Ubiquitin-like Protein Nedd8 Enhances the Activity of SCFskp2 toward p27kip1

โœ Scribed by Mitsuru Morimoto; Tamotsu Nishida; Reiko Honda; Hideyo Yasuda


Book ID
115585665
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
159 KB
Volume
270
Category
Article
ISSN
0006-291X

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## Abstract Myelin basic protein (MBP) is one of the major components of the myelin sheath that insulates axons. In the central nervous system, MBP is synthesized by differentiating oligodendrocytes. The expression of MBP in oligodendrocytes is regulated mainly at the transcriptional level. The Sp1