MODIFICATION OF CHROMOSOME BANDING TECHNIQUE
β Scribed by Irwin, Irene; Zoukis, Jeffrey; Mullick, Swadesh
- Book ID
- 123110562
- Publisher
- The Lancet
- Year
- 1973
- Tongue
- English
- Weight
- 147 KB
- Volume
- 301
- Category
- Article
- ISSN
- 0140-6736
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract We have developed spectral color banding (SCAN) as a new chromosome banding technique based on spectral analysis of differentially labeled chromosome bandβspecific painting probes. In this study, we succeeded in displaying a multicolor banding pattern for chromosome 3, which was almost
The interaction of Hoechst 33258 with DNA has been examined to help clarify the mechanisms of banding. 1. In agreement with previous studies Hoechst fluorescence is enhanced to a greater degree in AT-rich compared to GC-rich DNA. 2. Hoechst causes an increase in the DNA Tm which is greater at the hi
The binding of methylene blue to DNA and chromatin treated in various ways was examined by equilibrium dialysis. The maximum r value (moles of bound dye/mole of nucleotide) was 1.0 for DNA, 0.6 for unfixed chromatin, and 0.83 for chromatin fixed in methanol-acetic acid. When fixed chromatin was trea