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Modification by ageing of the tetrodotoxin-sensitive sodium channels in rat skeletal muscle fibres

✍ Scribed by Jean-François Desaphy; Annamaria De Luca; Paola Imbrici; Diana Conte Camerino


Book ID
117048989
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
697 KB
Volume
1373
Category
Article
ISSN
0005-2736

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Use dependence of sodium current inhibit
✍ Roland Eickhorn; Jörg Weirich; Daniela Hornung; Hermann Antoni 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 943 KB

Tetrodoxin (TTX) is known to cause a voltageand frequency-dependent inhibition of the rapid inward sodium current (IN,) of cardiac muscle. This effect was studied by means of the loose-patch-clamp method on intact rat papillary muscle. The availability curve of the fast sodium system, determined by