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Modification and functionalization of hydrogel microspheres

✍ Scribed by Haruma Kawaguchi; Keiji Fujimoto; Yoshiyuki Nakazawa; Mami Sakagawa; Yasushi Ariyoshi; Miwako Shidara; Hitoshi Okazaki; Yukio Ebisawa

Book ID: 103967394
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 688 KB
Volume: 109
Category: Article
ISSN: 0927-7757
DOI: 10.1016/0927-7757(95)03482-x

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## Abstract Microspheres made of poly(lactic‐__co__‐glycolic acid) (PLGA) are biocompatible and biodegradable, rendering them a promising tool in the context of drug delivery. However, nonspecific adsorption of plasma proteins on PLGA micro‐ and nanospheres is a main limitation of drug targeting. P