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Modern lipid-, carbohydrate-, and peptide-based delivery systems for peptide, vaccine, and gene products

✍ Scribed by Pavla Simerska; Peter M. Moyle; Istvan Toth

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
290 KB
Volume
31
Category
Article
ISSN
0198-6325

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✦ Synopsis

Abstract

Research related to peptide, vaccine, and gene delivery has grown exponentially over the last decade. In this review, we discuss the development of delivery systems for peptides, gene and vaccine products. Special focus is given to different lipidation and glycosylation strategies to improve the metabolic stability and membrane permeability of therapeutics, and their targeting to specific sites. The synthetic methods for preparation of the systems are also described. Β© 2009 Wiley Periodicals, Inc. Med Res Rev, 31, No. 4, 520–547, 2011

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