Background: Genetic predisposition as a cause of inflammatory bowel disease (IBD) has been proven by both family and twin studies and genetic variants associated with the disease have been identified. The aim of our study was to determine the concordance rates for IBD in German twin pairs and to eva
Modern epidemiology of anxiety: results of the Zurich cohort study
โ Scribed by Jules Angst
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 146 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0885-6222
No coin nor oath required. For personal study only.
โฆ Synopsis
The Zurich cohort study investigated a general population sample of 591 males and females, enriched by risk cases, through ยฎve interviews carried out between the ages of 20 and 35. The total prevalence rate for the anxiety spectrum (consisting of panic, general anxiety disorders (GAD) and recurrent brief anxiety states (RBA)) was 22 per cent. Panic and RBA were highly associated (odds ratio12 . 3). Complex panic syndromes ( panic GAD, panic RBA) were shown to be much more severe than pure panic in terms of impairment, treatment and suicide attempt rates. Pure panic, DSM-III GAD and RBA showed comparable validity. For the deยฎnition of GAD, a duration of two or four weeks is probably preferable to the 6-months currently required by DSM-IV and ICD-10. The marked longitudinal associations and diagnostic changes between the three anxiety states support the hypothesis of an anxiety spectrum.
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