Moderate G6PD deficiency increases mutation rates in the brain of mice
β Scribed by Klaus Felix; Lynne D Rockwood; Walter Pretsch; Jagadeesan Nair; Helmut Bartsch; Georg-Wilhelm Bornkamm; Siegfried Janz
- Book ID
- 114275076
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 206 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0891-5849
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Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common hereditary disorder in humans. Through a population study for G6PD deficiency using a cord blood quantitative G6PD assay in Bangkok, Thailand, we found that the prevalence of G6PD deficiency is 11.1% in Thai male (N=350) and 5.8%
## Abstract In this study, we investigated whether glucoseβ6βphosphate dehydrogenase (G6PD) promoter mutations are responsible for G6PD deficiency. We analysed the G6PD proximal promoter and the 5β² untranslated region (UTR) in 65 G6PDβdeficient individuals, in which no mutations have been found in