Modelling of the chromatographic separation of xylose-mannose in ion-exchange resin columns
โ Scribed by A. M. Wilhelm; G. Casamatta; T. Carillon; L. Rigal; A. Gaset
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 429 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1615-7605
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โฆ Synopsis
A mathematical model was proposed for the chromatographic separation of xylose and mannose on an ion-exchange resin in the Pb form: dispersion in the mobile phase, external mass transfer around the particles and internal diffusion were taken into account. Small-scale experiments provided an evaluation of the different parameters. Dispersion in the mobile phase was found to be the predominant phenomenon. The Peclet numbers were calculated by identification in the Laplace domain of the elution profiles. Influence of temperature and initial concentration of the sample were studied.
List of symbols
A m 2 C kg/m 3 C* C(s) -D mZ.s -1 Di f S-1
๐ SIMILAR VOLUMES
Methods for the column chromatographic analysis of neutral monosaccharides are based on three principles of separation: adsorption, partition between a water and organic phase, and ion-exchange. The chromatographic separations utilizing carbon columns and other adsorbents have been reviewed by Binkl