Retention modeling and simultaneous opti
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Yichu Shan; Ruihuan Zhao; Yukui Zhang; Weibing Zhang; Yan Tian
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Article
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2003
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John Wiley and Sons
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English
⚖ 436 KB
## Abstract A novel approach is proposed for the simultaneous optimization of mobile phase pH and gradient steepness in RP‐HPLC using artificial neural networks. By presetting the initial and final concentration of the organic solvent, a limited number of experiments with different gradient time an