Modelling for cost-effectiveness analysis

✍ Scribed by Louise B. Russell

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 83 KB
• Volume: 18
• Category: Article
• ISSN: 0277-6715
• DOI: 10.1002/(sici)1097-0258(19991215)18:23<3235::aid-sim313>3.0.co;2-6

✦ Synopsis

A model creates the framework for a cost-e!ectiveness analysis, allowing decision makers to explore the implications of using an intervention in di!erent ways and under di!erent conditions. To serve its purpose a model must produce accurate predictions and allow for substantial variation in the factors that in#uence costs and e!ects. This paper considers three aspects of modelling: validating e!ectiveness estimates; modelling costs; and the implications of common statistical forms. Validation procedures similar to those for e!ectiveness estimates are proposed for costs. Modellers need to pay more attention to ensuring that the pathway of events described by a model represents costs as well as it does e!ects. Modellers can also help improve the epidemiological and clinical research on which cost-e!ectiveness analyses depend by showing the implications for resource allocation of the statistical forms conventionally used in these "elds.