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Modelling expertise for structure elucidation in organic chemistry using Bayesian networks

✍ Scribed by Michaela Hohenner; Sven Wachsmuth; Gerhard Sagerer


Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
158 KB
Volume
18
Category
Article
ISSN
0950-7051

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Latent structure analysis in pharmaceuti
✍ Shingo Kikuchi; Yoshinori Onuki; Akihito Yasuda; Yoshihiro Hayashi; Kozo Takayam πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 594 KB

A latent structure analysis of pharmaceutical formulations was performed using Kohonen's self-organizing map (SOM) and a Bayesian network. A hydrophilic matrix tablet containing diltiazem hydrochloride (DTZ), a highly water-soluble model drug, was used as a model formulation. Nonlinear relationship