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Modeling the Yield of Double-Strand Breaks Due to Formation of Multiply Damaged Sites in Irradiated Plasmid DNA

โœ Scribed by Michael A. Xapsos and Wendy Knapp Pogozelski

Book ID
124681074
Publisher
Bioone
Year
1996
Tongue
English
Weight
992 KB
Volume
146
Category
Article
ISSN
0033-7587

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โœ Bradley, Matthews O. ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 341 KB ๐Ÿ‘ 1 views

## Abstract DNA DSBs are formed in normal human IMRโ€90 cells during repair incubation after 100 and 300 Jยทm^โˆ’2^ of UVL. By contrast, no DSBs are formed after UVL in human XPA cells that are unable to excise pyrimidine dimers. The DSBs are not due to immediate cell death since all the cells excluded