Modeling the Heart and the Circulatory System

✍ Scribed by Alfio Quarteroni (eds.)

• Publisher: Springer International Publishing
• Year: 2015
• Tongue: English
• Leaves: 248
• Series: MS&A 14
• Edition: 1
• Category: Library

✦ Synopsis

The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. The contributions cover a wide range of topics, from the preprocessing of clinical data to the development of mathematical equations, their numerical solution, and both in-vivo and in-vitro validation. They discuss the flow in the systemic arterial tree and the complex electro-fluid-mechanical coupling in the human heart. Many examples of patient-specific simulations are presented. This book is addressed to all scientists interested in the mathematical modeling and numerical simulation of the human cardiocirculatory system.

✦ Table of Contents

Front Matter....Pages i-xiv
Cardiac Arrhythmias: Mechanistic Knowledge and Innovation from Computer Models....Pages 1-27
Discrete Mechanical Modeling of Mechanoelectrical Feedback in Cardiac Tissue: Novel Mechanisms of Spiral Wave Initiation....Pages 29-50
Multiscale Modelling of Cardiac Perfusion....Pages 51-96
Using Image-based CFD to Investigate the Intracardiac Turbulence....Pages 97-117
Multiscale Modeling of Sickle Cell Anemia....Pages 119-156
A Three-dimensional Continuum Model of Active Contraction in Single Cardiomyocytes....Pages 157-176
On the Assumption of Laminar Flow in Physiological Flows: Cerebral Aneurysms as an Illustrative Example....Pages 177-195
Effects of Poroelasticity on Fluid-Structure Interaction in Arteries: a Computational Sensitivity Study....Pages 197-220
Personalized Anatomical Meshing of the Human Body with Applications....Pages 221-236
Back Matter....Pages 237-238

✦ Subjects

Physiological, Cellular and Medical Topics; Human Physiology; Appl.Mathematics/Computational Methods of Engineering; Systems Biology