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MODELING THE EQUILIBRIUM STATE OF ADHERENT CELLS

✍ Scribed by Robert W. Metzke; Mohammad R.K. Mofrad; Wolfgang A. Wall


Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
77 KB
Volume
41
Category
Article
ISSN
0021-9290

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The behavior of normal adherent cells is influenced by the stiffness of the substrate they are anchored to. Cells are able to detect substrate mechanical properties by actively generating contractile forces and use this information to migrate and proliferate. In particular, the speed and direction o