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Modeling skin permeability to hydrophilic and hydrophobic solutes based on four permeation pathways

โœ Scribed by Samir Mitragotri


Book ID
114161981
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
579 KB
Volume
86
Category
Article
ISSN
0168-3659

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โœ Samir Mitragotri ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 125 KB

A number of studies have reported on the activation energies of skin permeability. In this article, I summarize the literature data on activation energies and analyze their dependence on solute molecular properties, namely radius and lipophilicity. Theoretical equations are also presented to facilit