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Modeling of the whole CFTR 3D structure and its conformational transitions

✍ Scribed by J.P. Mornon; P. Lehn; I. Callebaut


Book ID
118642076
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
56 KB
Volume
8
Category
Article
ISSN
1569-1993

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Modeling the 3D structure of GPCRs from
✍ Sharon Shacham; Maya Topf; Noa Avisar; Fabian Glaser; Yael Marantz; Shay Bar-Hai πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 377 KB πŸ‘ 1 views

## Abstract G‐protein‐coupled receptors (GPCRs) are a large and functionally diverse protein superfamily, which form a seven transmembrane (TM) helices bundle with alternating extra‐cellular and intracellular loops. GPCRs are considered to be one of the most important groups of drug targets because