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Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts

✍ Scribed by P. Cottu, E. Marangoni, F. Assayag, P. de Cremoux, A. Vincent-Salomon, Ch. Guyader, L. de Plater, C. Elbaz, N. Karboul, J. J. Fontaine, S. Chateau-Joubert, P. Boudou-Rouquette, S. Alran, V. Dangles-Marie, D. Gentien, et al


Book ID
113062320
Publisher
Springer US
Year
2011
Tongue
English
Weight
870 KB
Volume
133
Category
Article
ISSN
0167-6806

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This review presents our experience with the use of estrogen receptors (ER) and progesterone receptors (PgR) in the prediction of response to endocrine therapy in stage IV breast cancer. Presence of ER (>3 fmoUmg cytosol protein) significantly predicted response to the antiestrogen tamoxifen and to