We discuss analyses of the Genetic Analysis Workshop 13 data from the Framingham Heart Study and simulations based on this study. We summarize analyses that investigated measures of systolic blood pressure or hypertension as the main phenotype, with the main focus being the modeling of this complex
✦ LIBER ✦
Modeling of multivariate longitudinal phenotypes in family genetic studies with Bayesian multiplicity adjustment
✍ Scribed by Lili Ding,Brad G Kurowski,Hua He,Eileen S Alexander,Tesfaye B Mersha…
- Book ID
- 126380079
- Publisher
- BioMed Central
- Year
- 2014
- Tongue
- English
- Weight
- 538 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1753-6561
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## Abstract ## Objective The contribution of genetics to osteoarthritis (OA) progression is not known. To gain more insight into whether familial factors play a role in disease progression of OA, we analyzed familial aggregation of radiologic OA progression in a study of sibling pairs (the Genetic