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Modeling of human tumor xenografts and dose rationale in oncology

โœ Scribed by Simeoni, Monica; De Nicolao, Giuseppe; Magni, Paolo; Rocchetti, Maurizio; Poggesi, Italo


Book ID
122457805
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
865 KB
Volume
10
Category
Article
ISSN
1740-6749

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This study investigates the influence of antibody protein dose on the radioimmunodetection of a CEA-producing, human colonic tumor xenograft (GW-39) using affinity-purified goat anti-carcinoembryonic antigen (CEA) antibody and a murine monoclonal anti-CEA antibody (NP-2). Hamsters bearing GW-39 tumo