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Modeling of Folding and Unfolding Mechanisms in Alanine-Based α-Helical Polypeptides

✍ Scribed by Morozov, Alexander N.; Lin, Sheng Hsien


Book ID
121295137
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
82 KB
Volume
110
Category
Article
ISSN
0022-3654

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## Abstract The presence of non‐native kinetic traps in the free energy landscape of a protein may significantly lengthen the overall folding time so that the folding process becomes unreliable. We use a computational model α‐helical hairpin peptide to calculate structural free energy landscapes an