Modeling of biological reactions

✍ Scribed by Shao-mu Ma; Henry Eyring; Issaku Ueda; Shoji Kaneshina

• Book ID: 102926599
• Publisher: John Wiley and Sons
• Year: 1981
• Tongue: English
• Weight: 527 KB
• Volume: 13
• Category: Article
• ISSN: 0538-8066
• DOI: 10.1002/kin.550130914

✦ Synopsis

Abstract

Cell membranes consist of lipid bilayers in which proteins are embedded. Many cell functions are carried out at the cell boundary which interface with water. Here we describe the response to an anesthetic of a lipid bilayer and of an enzyme separately. While both systems are markedly affected by anesthetics at appropriately high concentrations, the result at the clinical concentrations seems best explained as principally an effect on the protein somewhat accentuated by its presence in the lipid bilayer. Thus the lipoprotein complex seems to have the properties of the protein alone, except with somewhat greater induced sensitivity due to the lipid matrix in which it is immersed.