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Modeling Noncompetitive Antagonism of a Nicotinic Acetylcholine Receptor

✍ Scribed by Tikhonov, Denis B.; Mellor, Ian R.; Usherwood, Peter N.R.


Book ID
119988783
Publisher
Biophysical Society
Year
2004
Tongue
English
Weight
520 KB
Volume
87
Category
Article
ISSN
0006-3495

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Over the past few decades much effort has been expended elucidating the key domains of the nicotinic acetylcholine receptor (AChR) responsible for agonist binding, ion conduction, and gating. An emerging concept in the receptor field has been to consider the receptor entity as a signal transducer th