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Modeling influenza sequence evolution for vaccination

✍ Scribed by Taijiao Jiang

Book ID
120684717
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
62 KB
Volume
6
Category
Article
ISSN
1753-6561

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Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability? To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the