Usually, in teratological dose finding studies, there are not only threshold effects but also extra variations that cannot be accounted for by the beta-binomial model alone. The beta-binomial model assumes correlation between fetuses in the same litter. The general random effect threshold (RE) model
β¦ LIBER β¦
Modeling developmental data using U-shaped threshold dose-response curves
β Scribed by Hunt, Daniel; Bowman, Dale
- Book ID
- 126638719
- Publisher
- Taylor and Francis Group
- Year
- 2006
- Tongue
- English
- Weight
- 156 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0266-4763
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A new threshold dose-response model incl
β
Daniel L. Hunt; Shesh N. Rai
π
Article
π
2005
π
John Wiley and Sons
π
English
β 115 KB
Testing Threshold and Hormesis in a Rand
β
D. Hunt; S. N. Rai
π
Article
π
2005
π
John Wiley and Sons
π
English
β 137 KB
π 1 views
Here we describe a random effects threshold dose-response model for clustered binary-response data from developmental toxicity studies. For our model we assume that a hormetic effect occurs in addition to a threshold effect. Therefore, the dose-response curve is based on two components: relationship
The Use of In Vitro Toxicity Data and Ph
β
Louisse, J.; de Jong, E.; van de Sandt, J. J. M.; Blaauboer, B. J.; Woutersen, R
π
Article
π
2010
π
Oxford University Press
π
English
β 446 KB
The use of non-linear regression analysi
β
William G. Bardsley; Philip B. McGinlay
π
Article
π
1987
π
Elsevier Science
π
English
β 722 KB
Poster #221 EXPLORING THE BIOLOGY OF THE
β
Hugo Geerts; Patrick Roberts; Γthan Spiros
π
Article
π
2012
π
Elsevier Science
π
English
β 66 KB
Combining in vitro embryotoxicity data w
β
Strikwold, Marije; Spenkelink, Bert; Woutersen, Ruud A.; Rietjens, Ivonne M. C.
π
Article
π
2013
π
Springer-Verlag
π
English
β 365 KB