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Modeling Alzheimer's disease in transgenic mice: effect of age and of Presenilin1 on amyloid biochemistry and pathology in APP/London mice

✍ Scribed by I Dewachter; J van Dorpe; K Spittaels; I Tesseur; C Van Den Haute; D Moechars; F Van Leuven

Book ID
114253459
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
237 KB
Volume
35
Category
Article
ISSN
0531-5565

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## Abstract ## Purpose To investigate the relationship between MR image contrast associated with beta‐amyloid (AΞ²) plaques and their histology and compare the histopathological basis of image contrast and the relaxation mechanism associated with AΞ² plaques in human Alzheimer's disease (AD) and tra